This new type of pulse diagnostic system is based on measurement and analysis of the radial artery sphygmograms. This system has new type of pulse wave detector, mathematical method designed to ensure accuracy and reliability of measurements and method for interpreting the characteristics of the sphygmograms. This diagnostic system PULS-AS provides an opportunity to objectively evaluate the response of an individual body to the course of chronic processes; the adaptation of the body to the medicine/drugs; the adaptation to physical activity; the body’s response to changes in the daily regime and diet; the body’s response to resort spa treatment and recreational effects. It is also possible to follow the process fluctuations and the state of the healthy body before the illness manifests itself, to objectify subclinical conditions. The features of this new diagnostic system PULS-AS allow to substantially expand its circle of users.